Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21122490 | 1.00 | PTPN1 (0.54) | PTPN1TAAR1TSHRMAPK1LMNA | |
| SCHEMBL30866423 | 0.88 | CYP19A1 (0.49) | ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21156703 | 0.88 | CYP19A1 (0.49) | ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28417902 | 0.85 | AKR1B1 (0.47) | PTPN1ALOX5ADRB2GAAAKR1B1 | |
| SCHEMBL21121434 | 0.80 | HDAC1 (0.35) | — | |
| SCHEMBL17780116 | 0.78 | PTPN1 (0.82) | PTPN1TAAR1TSHRMAPK1LMNA | |
| SCHEMBL29604390 | 0.78 | PTPN1 (0.82) | PTPN1TAAR1TSHRMAPK1LMNA | |
| SCHEMBL21157986 | 0.77 | RAB9A (0.48) | TAAR1LMNAALDH1A1TDP1CALM1 | |
| SCHEMBL22554343 | 0.76 | F2 (0.39) | — | |
| SCHEMBL30866426 | 0.76 | F2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |