Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866420 | 0.85 | PTPN1 (0.54) | AKR1B1ALOX5PTPN1ADRB2GAA | |
| SCHEMBL21122490 | 0.85 | PTPN1 (0.54) | AKR1B1ALOX5PTPN1ADRB2GAA | |
| SCHEMBL30866423 | 0.83 | CYP19A1 (0.49) | KDM4ECA2 | |
| SCHEMBL21156703 | 0.83 | CYP19A1 (0.49) | KDM4ECA2 | |
| SCHEMBL21121171 | 0.81 | PTGS1 (0.42) | PTGS1PTGS2KDM4EGAACA1 | |
| SCHEMBL28412859 | 0.78 | TDP2 (0.33) | PTPN1 | |
| SCHEMBL22554343 | 0.77 | F2 (0.39) | — | |
| SCHEMBL30866426 | 0.77 | F2 (0.39) | — | |
| SCHEMBL16372690 | 0.76 | AKR1B1 (0.71) | AKR1B1ALOX5TNKS2METKDM4E | |
| SCHEMBL21157986 | 0.75 | RAB9A (0.48) | KDM4ETUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170918-B | Method for synthesizing gamma-lactam and delta-lactam through C-H amine | 山东大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-111170918-A | Method for synthesizing gamma-lactam and delta-lactam through C-H amine | 山东大学 | 2020-05-19 | — | — | CN | disclosed |