Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.58 |
| ▸ | CNR1 | P21554 | 5/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910232 | 0.90 | CNR2 (0.58) | CNR2CNR1PPARA | |
| SCHEMBL3081610 | 0.88 | CNR2 (0.48) | CNR2CNR1PPARA | |
| SCHEMBL4914114 | 0.87 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL908310 | 0.87 | CNR2 (0.75) | CNR2CNR1PPARA | |
| SCHEMBL3081674 | 0.84 | CNR1 (0.72) | CNR2CNR1PPARA | |
| SCHEMBL4912598 | 0.82 | CNR1 (0.51) | CNR2CNR1 | |
| SCHEMBL4910785 | 0.82 | CNR2 (0.47) | CNR2CNR1PPARA | |
| SCHEMBL4893928 | 0.81 | CNR1 (0.66) | CNR2CNR1 | |
| SCHEMBL4773336 | 0.80 | CNR1 (0.64) | CNR2CNR1 | |
| SCHEMBL4910447 | 0.79 | PDE4B (0.47) | CNR2CNR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234439-A1 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2010-09-16 | — | — | US | disclosed |
| US-20100234438-A1 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2010-09-16 | — | — | US | disclosed |
| US-20080146614-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234439-A1 | THERAPEUTIC AGENTS | NLN, GPR119, GRIK5 | CNR2 148/4885CNR1 185/4885PPARA 104/4885 |
| US-20080146614-A1 | Therapeutic Agents | BDNF, NLN, GRIN2C | CNR2 480/4885CNR1 597/4885PPARA 509/4885 |
| US-20100234438-A1 | THERAPEUTIC AGENTS | NLN, GPR119, GRIK5 | CNR2 148/4885CNR1 185/4885PPARA 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.