Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318910 | 1.00 | MTNR1A (0.41) | MTNR1ANQO1CDK2CCNT1CCNA2 | |
| SCHEMBL30867175 | 0.89 | NQO1 (0.46) | NQO1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL27318674 | 0.89 | NQO1 (0.46) | NQO1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL27319295 | 0.88 | NQO1 (0.39) | NQO1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL30867193 | 0.88 | NQO1 (0.39) | NQO1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL27318928 | 0.86 | MTNR1A (0.43) | MTNR1ANQO1CDK2CCNT1CCNA2 | |
| SCHEMBL31534081 | 0.86 | MTNR1A (0.37) | MTNR1ANQO1CDK2CCNT1CCNA2 | |
| SCHEMBL27319322 | 0.86 | MTNR1A (0.37) | MTNR1ANQO1CDK2CCNT1CCNA2 | |
| SCHEMBL27319983 | 0.83 | CYP1A2 (0.43) | MTNR1AUSP2TP53CYP1A2CYP3A4 | |
| SCHEMBL27319910 | 0.83 | ALDH1A1 (0.42) | MTNR1AUSP2TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |