Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27319867 | 1.00 | HTR2A (0.45) | HTR2ATRPM8GPR84SLC6A4CDK4 | |
| SCHEMBL30867130 | 0.90 | MPO (0.44) | HTR2ATRPM8GPR84SLC6A4HTR1A | |
| SCHEMBL27319943 | 0.90 | MPO (0.44) | HTR2ATRPM8GPR84SLC6A4HTR1A | |
| SCHEMBL30867180 | 0.87 | SSTR2 (0.43) | HTR2AGPR84SLC6A4HTR1ADRD2 | |
| SCHEMBL27318935 | 0.87 | SSTR2 (0.43) | HTR2AGPR84SLC6A4HTR1ADRD2 | |
| SCHEMBL27320810 | 0.86 | SNCA (0.41) | HTR2ATRPM8GPR84SLC6A4CDK4 | |
| SCHEMBL30867161 | 0.86 | SNCA (0.41) | HTR2ATRPM8GPR84SLC6A4CDK4 | |
| SCHEMBL30867131 | 0.85 | HTR2A (0.39) | HTR2ATRPM8GPR84SLC6A4CDK4 | |
| SCHEMBL30867191 | 0.85 | SNCA (0.40) | HTR2ATRPM8GPR84SLC6A4CDK4 | |
| SCHEMBL27320677 | 0.85 | HTR2A (0.39) | HTR2ATRPM8GPR84SLC6A4CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| CN-119948035-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |