Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867161 | 1.00 | SNCA (0.41) | SNCAHTR2ATRPM8SLC6A4HTR1A | |
| SCHEMBL30867191 | 0.94 | SNCA (0.40) | SNCAHTR2ATRPM8SLC6A4HTR1A | |
| SCHEMBL27319951 | 0.88 | MPO (0.42) | HTR2ATRPM8SLC6A4HTR1AGPR84 | |
| SCHEMBL30867157 | 0.88 | MPO (0.42) | HTR2ATRPM8SLC6A4HTR1AGPR84 | |
| SCHEMBL30867211 | 0.87 | HTR1A (0.43) | HTR2ATRPM8SLC6A4HTR1AMPO | |
| SCHEMBL27319956 | 0.87 | HTR1A (0.43) | HTR2ATRPM8SLC6A4HTR1AMPO | |
| SCHEMBL31534055 | 0.87 | MPO (0.42) | HTR2ATRPM8SLC6A4HTR1AGPR84 | |
| SCHEMBL27320817 | 0.87 | MPO (0.42) | HTR2ATRPM8SLC6A4HTR1AGPR84 | |
| SCHEMBL31534073 | 0.87 | CDK4 (0.43) | SLC6A4HTR1AGPR84CDK4CCND1 | |
| SCHEMBL27319565 | 0.87 | CDK4 (0.43) | SLC6A4HTR1AGPR84CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |