Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 13/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867131 | 0.89 | HTR2A (0.39) | HTR2ATRPM8SLC6A4HTR1AGPR84 | |
| SCHEMBL27320677 | 0.89 | HTR2A (0.39) | HTR2ATRPM8SLC6A4HTR1AGPR84 | |
| SCHEMBL27320797 | 0.87 | GSK3B (0.40) | MPOHTR2ASLC6A4HTR1AKMT2A | |
| SCHEMBL31534065 | 0.87 | GSK3B (0.40) | MPOHTR2ASLC6A4HTR1AKMT2A | |
| SCHEMBL30867155 | 0.87 | MPO (0.40) | MPOHTR2ATRPM8SLC6A4HTR1A | |
| SCHEMBL27320599 | 0.87 | MPO (0.40) | MPOHTR2ATRPM8SLC6A4HTR1A | |
| SCHEMBL31534055 | 0.86 | MPO (0.42) | MPOHTR2ATRPM8SLC6A4HTR1A | |
| SCHEMBL27320817 | 0.86 | MPO (0.42) | MPOHTR2ATRPM8SLC6A4HTR1A | |
| SCHEMBL30867157 | 0.86 | MPO (0.42) | MPOHTR2ATRPM8SLC6A4HTR1A | |
| SCHEMBL27319951 | 0.86 | MPO (0.42) | MPOHTR2ATRPM8SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| CN-119948035-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |