Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | NEK4 | P51957 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31534065 | 1.00 | GSK3B (0.40) | GSK3BNEK4CSNK2A1CLK4SSTR2 | |
| SCHEMBL30867131 | 0.87 | HTR2A (0.39) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL30867173 | 0.87 | MPO (0.40) | HTR1AHTR2AMPOKMT2ASLC6A4 | |
| SCHEMBL27320677 | 0.87 | HTR2A (0.39) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL31534056 | 0.86 | GBA1 (0.41) | GSK3BNEK4CSNK2A1CLK4SSTR2 | |
| SCHEMBL31534073 | 0.85 | CDK4 (0.43) | GSK3BSSTR2SSTR4HTR1ASLC6A4 | |
| SCHEMBL27319565 | 0.85 | CDK4 (0.43) | GSK3BSSTR2SSTR4HTR1ASLC6A4 | |
| SCHEMBL30867195 | 0.84 | PTGS2 (0.40) | GSK3BNEK4CSNK2A1CLK4SSTR2 | |
| SCHEMBL27319333 | 0.84 | PTGS2 (0.40) | GSK3BNEK4CSNK2A1CLK4SSTR2 | |
| SCHEMBL30867203 | 0.83 | SSTR2 (0.39) | GSK3BNEK4CSNK2A1CLK4SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |