SCHEMBL30867178

SCHEMBL30867178

Clc1nc(NCCc2c[nH]c3ncccc23)c2ncsc2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.45
GPR84 Q9NQS5 1/20 0.43
CDK2 P24941 5/20 0.42
CCNT1 O60563 2/20 0.42
CCNA2 P20248 2/20 0.42
CDK9 P50750 2/20 0.42
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MET P08581 1/20 0.39
AURKA O14965 1/20 0.38
HTR6 P50406 2/20 0.37
NSD2 O96028 1/20 0.37
GBA1 P04062 1/20 0.37
DRD2 P14416 3/20 0.37
DRD4 P21917 3/20 0.37
DRD3 P35462 3/20 0.37
HDAC1 Q13547 1/20 0.37
CCNE1 P24864 3/20 0.36
CACNA1F O60840 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27318895 1.00 MTNR1A (0.45) MTNR1AGPR84CDK2CCNT1CCNA2
SCHEMBL30867135 0.86 HTT (0.49) GPR84NPC1RAB9AHTR6NSD2
SCHEMBL30867137 0.86 HTT (0.49) GPR84NPC1RAB9AHTR6NSD2
SCHEMBL27318656 0.86 HTT (0.49) GPR84NPC1RAB9AHTR6NSD2
SCHEMBL27319288 0.85 NPC1 (0.39) CDK2CCNT1CCNA2CDK9NPC1
SCHEMBL30867166 0.85 NPC1 (0.39) CDK2CCNT1CCNA2CDK9NPC1
SCHEMBL27318928 0.82 MTNR1A (0.43) MTNR1AGPR84CDK2CCNT1CCNA2
SCHEMBL30867167 0.81 GPR84 (0.43) MTNR1AGPR84CDK2METHTR6
SCHEMBL27319316 0.81 GPR84 (0.43) MTNR1AGPR84CDK2METHTR6
SCHEMBL30867205 0.80 IP6K1 (0.49) MTNR1AGPR84TSHRHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598931-A1 COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING JAGUAHR THERAPEUTICS PTE LTD (SG) 2025-08-13 EP disclosed
CN-119948035-A Compounds useful for modulating AhR signaling 捷豹治疗有限公司 2025-05-06 CN disclosed
WO-2024076300-A1 COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING JAGUAHR THERAPEUTICS PTE LTD (SG) 2024-04-11 WO disclosed