Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | NEK4 | P51957 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
| ▸ | CCND1 | P24385 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867168 | 0.93 | CDK4 (0.41) | GSK3BNEK4CSNK2A1CLK4NAMPT | |
| SCHEMBL31534062 | 0.92 | CDK4 (0.43) | GSK3BNEK4CSNK2A1CLK4NAMPT | |
| SCHEMBL31534077 | 0.87 | GBA1 (0.41) | GSK3BNEK4CSNK2A1CLK4SSTR4 | |
| SCHEMBL31534063 | 0.85 | HTR1A (0.43) | KMT2AHTR1ASLC6A4 | |
| SCHEMBL30867182 | 0.81 | SSTR2 (0.43) | GSK3BNEK4CSNK2A1CLK4SSTR4 | |
| SCHEMBL30867181 | 0.81 | SSTR2 (0.43) | GSK3BNEK4CSNK2A1CLK4SSTR4 | |
| SCHEMBL31534067 | 0.76 | MPO (0.41) | KMT2AHTR1ASLC6A4 | |
| SCHEMBL31534096 | 0.76 | GSK3B (0.39) | GSK3BNEK4CSNK2A1CLK4NAMPT | |
| SCHEMBL27319549 | 0.76 | GSK3B (0.39) | GSK3BNEK4CSNK2A1CLK4NAMPT | |
| SCHEMBL31534086 | 0.73 | HTR1A (0.39) | CDK4CCND1MEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |