Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916290 | 0.85 | HSD17B10 (0.40) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL27516238 | 0.83 | HSD17B10 (0.42) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL27443087 | 0.83 | HSD17B10 (0.42) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL27439612 | 0.83 | HSD17B10 (0.42) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL24757382 | 0.77 | HSD17B10 (0.40) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL22251831 | 0.77 | HSD17B10 (0.40) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL7355124 | 0.77 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL15430147 | 0.76 | HSD17B10 (0.47) | HSD17B10HPGDSMN1; SMN2USP2EPHX1 | |
| SCHEMBL16589502 | 0.76 | HSD17B10 (0.47) | HSD17B10HPGDSMN1; SMN2USP2EPHX1 | |
| SCHEMBL9977348 | 0.76 | HSD17B10 (0.47) | HSD17B10HPGDSMN1; SMN2USP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993850-B | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2024-03-29 | — | — | CN | disclosed |