Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867287 | 0.84 | KDM4E (0.43) | KDM4ELMNAPKMIDO1ALDH1A1 | |
| SCHEMBL10373408 | 0.79 | KDM4E (0.48) | KDM4ELMNAPKMIDO1RAB9A | |
| SCHEMBL6733600 | 0.78 | KDM4E (0.45) | KDM4ELMNAPKMIDO1ALDH1A1 | |
| SCHEMBL14783264 | 0.77 | KDM4E (0.50) | KDM4ELMNAPKMIDO1HSD17B10 | |
| SCHEMBL14967259 | 0.77 | KDM4E (0.47) | KDM4ELMNAPKMIDO1RAB9A | |
| SCHEMBL2371687 | 0.76 | KDM4E (0.55) | KDM4ELMNAPKMIDO1RAB9A | |
| SCHEMBL10370830 | 0.76 | KDM4E (0.55) | KDM4ELMNAPKMIDO1RAB9A | |
| SCHEMBL9726366 | 0.76 | KDM4E (0.50) | KDM4ELMNAPKMIDO1RAB9A | |
| SCHEMBL14966711 | 0.75 | KDM4E (0.50) | KDM4ELMNAPKMIDO1RAB9A | |
| SCHEMBL10373414 | 0.74 | KDM4E (0.44) | KDM4ELMNAPKMIDO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054622-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |