Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATF1 | P18846 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867279 | 0.84 | KDM4E (0.50) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL10373408 | 0.80 | KDM4E (0.48) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL6733600 | 0.79 | KDM4E (0.45) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL10370416 | 0.77 | KDM4E (0.48) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL9726366 | 0.77 | KDM4E (0.50) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL10373414 | 0.75 | KDM4E (0.44) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL30867520 | 0.74 | ALDH1A1 (0.40) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL31426629 | 0.74 | ALDH1A1 (0.40) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL30867525 | 0.74 | ALDH1A1 (0.40) | KDM4EMAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL25387538 | 0.74 | KDM4E (0.42) | KDM4EMAPTPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054622-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |