Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30562612 | 0.84 | MAPT (0.43) | SMN1; SMN2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL25388587 | 0.84 | MAPT (0.43) | SMN1; SMN2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL24683112 | 0.74 | CA12 (0.40) | ALDH1A1KMT2AKDM4EMAPK1TSHR | |
| SCHEMBL18038271 | 0.74 | MAPK1 (0.57) | MAPTALDH1A1KMT2AKDM4EMAPK1 | |
| SCHEMBL22575988 | 0.74 | GPR35 (0.41) | SMN1; SMN2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL17084499 | 0.74 | GPR35 (0.41) | SMN1; SMN2ALDH1A1KMT2ATSHRTDP1 | |
| SCHEMBL1584481 | 0.73 | TSHR (0.46) | SMN1; SMN2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL10473496 | 0.73 | TSHR (0.43) | ALDH1A1TSHRTDP1POLBCA1 | |
| SCHEMBL25386991 | 0.73 | OPRK1 (0.43) | SMN1; SMN2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL30562742 | 0.73 | OPRK1 (0.43) | SMN1; SMN2MAPTALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-119894509-A | Sodium channel blocking compounds, derivatives thereof, and methods of use thereof | 拉堤果生物医疗股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024054622-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |