Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | SCN8A | Q9UQD0 | 13/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 13/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867489 | 0.88 | KDM4E (0.54) | SCN8ASCN10AMRGPRX4KDM4EUSP2 | |
| SCHEMBL31426521 | 0.87 | SCN8A (0.44) | CFTRSCN8ASCN10AKDM4EUSP2 | |
| SCHEMBL24518270 | 0.81 | SCN10A (0.61) | CFTRSCN8ASCN10A | |
| SCHEMBL30867500 | 0.81 | RAF1 (0.40) | CFTRMRGPRX4ALDH1A1HPGD | |
| SCHEMBL24901813 | 0.76 | CFTR (0.67) | CFTRMRGPRX4KDM4EUSP2ALDH1A1 | |
| SCHEMBL30867347 | 0.76 | NOTUM (0.37) | SCN8ASCN10AMRGPRX4KDM4EALDH1A1 | |
| SCHEMBL30867436 | 0.75 | SCN10A (0.41) | SCN8ASCN10AMRGPRX4KDM4EALDH1A1 | |
| SCHEMBL31426654 | 0.74 | SCN8A (0.51) | SCN8ASCN10A | |
| SCHEMBL9956693 | 0.74 | RAB9A (0.62) | CFTRKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL31565499 | 0.74 | RAB9A (0.62) | CFTRKDM4EALDH1A1HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054622-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |