Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 8/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31426521 | 0.89 | SCN8A (0.44) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL30867386 | 0.88 | CFTR (0.50) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL4661838 | 0.80 | SCN8A (0.62) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL31426525 | 0.80 | NOTUM (0.40) | ALDH1A1HPGDSORT1MRGPRX4 | |
| SCHEMBL24518269 | 0.80 | SCN10A (0.61) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL29571346 | 0.80 | SCN10A (0.61) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL31426654 | 0.74 | SCN8A (0.51) | SCN8ASCN10A | |
| SCHEMBL31426573 | 0.73 | L3MBTL1 (0.35) | KDM4EALDH1A1SORT1SCN10A | |
| SCHEMBL30867514 | 0.73 | SCN10A (0.38) | KDM4EALDH1A1SORT1SCN8ASCN10A | |
| SCHEMBL422034 | 0.73 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-119894509-A | Sodium channel blocking compounds, derivatives thereof, and methods of use thereof | 拉堤果生物医疗股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024054622-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |