Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459178 | 0.84 | ALDH1A1 (0.42) | HSD17B10 | |
| SCHEMBL3450931 | 0.84 | ALDH1A1 (0.42) | HSD17B10 | |
| SCHEMBL27448979 | 0.81 | POLB (0.50) | POLBSIRT6TSHRNNMTCYP2C9 | |
| SCHEMBL28475154 | 0.81 | POLB (0.46) | POLBSIRT6TSHRNNMTCYP2C9 | |
| SCHEMBL27344813 | 0.81 | POLB (0.34) | POLBSIRT6TSHRNNMTADORA3 | |
| SCHEMBL24683791 | 0.79 | TSHR (0.37) | TSHRHSD17B10MAPT | |
| SCHEMBL28883340 | 0.79 | CNR1 (0.32) | POLBADORA3 | |
| SCHEMBL4144902 | 0.79 | POLB (0.43) | POLBSIRT6TSHRNNMTCYP2C9 | |
| Hydrochloric Acid SCHEMBL5253403 | 0.79 | PIK3CB (0.35) | POLBTSHRNNMTADORA3MC4R | |
| Nitrous Acid SCHEMBL28883343 | 0.78 | ALDH1A1 (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054622-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |