⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261813 | 0.80 | — | — | |
| SCHEMBL8786624 | 0.79 | KMT2A (0.59) | — | |
| SCHEMBL5592700 | 0.77 | HDAC6 (0.44) | — | |
| SCHEMBL1031249 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL8507209 | 0.75 | ALDH1A1 (0.41) | — | |
| Isonicotinic Acid SCHEMBL1414914 | 0.67 | NAPRT (1.00) | — | |
| Isonicotinic Acid SCHEMBL1108 | 0.67 | — | — | |
| Isonicotinic Acid SCHEMBL25269381 | 0.65 | NAPRT (0.94) | — | |
| Isonicotinic Acid SCHEMBL25270920 | 0.65 | NAPRT (0.94) | — | |
| Isonicotinic Acid SCHEMBL25273146 | 0.65 | NAPRT (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-09-07 | — | — | US | claimed |
| CN-108884029-B | LSD1 inhibitors | 米拉蒂医疗股份有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-110746479-B | Compound and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | claimed |
| EP-3397616-B1 | LSD1 INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2020-06-10 | — | — | EP | claimed |
| CN-110746479-A | Compound and preparation method and application thereof | 山东师范大学 | 2020-02-04 | — | — | CN | claimed |
| US-10233152-B2 | LSD1 inhibitors | Mirati Therapeutics, Inc. (US) | 2019-03-19 | — | — | US | claimed |
| EP-3397616-A1 | LSD1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2018-11-07 | — | — | EP | claimed |
| US-20180127369-A1 | LSD1 Inhibitors | Mirati Therapeutics, Inc. | 2018-05-10 | — | — | US | claimed |
| US-9809541-B2 | LSD1 inhibitors | Mirati Therapeutics, Inc. (US) | 2017-11-07 | — | — | US | claimed |
| WO-2017116558-A1 | LSD1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-07-06 | — | — | WO | claimed |
| US-20030199565-A1 | Gastrin and cholecystokinin receptor ligands(II) | JAMES BLACK FOUNDATION LIMITED (GB) | 2003-10-23 | — | — | US | claimed |
| US-20030069291-A1 | 3-heterocyclylpropanohydroxamic acid PCP inhibitors | PFIZER INC. | 2003-04-10 | — | — | US | claimed |
| WO-2002079200-A1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LIMITED (GB) | 2002-10-10 | — | — | WO | claimed |
| WO-2001085723-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS (II) | JAMES BLACK FOUNDATION LIMITED (GB) | 2001-11-15 | — | — | WO | claimed |
| US-6245988-B1 | USEFUL IN A PHOTOVOLTAIC CELL COMPRISING A NANOCRYSTALLINE TITANIUM DIOXIDE LAYER; IMPROVING THE EFFICIENCY OF SOLAR TO ELECTRIC POWER CONVERSION BY PROVIDING PHOTOSENSITIZER HAVING ENHANCED SPECTRAL RESPONSE IN RED/INFRARED REGIONS | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2001-06-12 | — | — | US | claimed |
| EP-0983282-A1 | METAL COMPLEX PHOTOSENSITIZER AND PHOTOVOLTAIC CELL | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2000-03-08 | — | — | EP | claimed |
| WO-1998050393-A1 | METAL COMPLEX PHOTOSENSITIZER AND PHOTOVOLTAIC CELL | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 1998-11-12 | — | — | WO | claimed |
| US-5811081-A | Use of hydroxybenzotriazoles for enhancing the sun protection factor of cellulosic fibre materials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-22 | — | — | US | claimed |
| EP-0708197-A2 | Utilisation of hydroxybenztriazoles for increasing the sun-ray filter index of fibrous cellulosic materials | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | claimed |
| US-5466571-A | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1995-11-14 | — | — | US | claimed |