SCHEMBL30867646

SCHEMBL30867646

O=C(O)c1ccc2ccccc2c1Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.46
PPARG P37231 5/20 0.46
PPARA Q07869 3/20 0.46
LDHA P00338 1/20 0.45
CXCR2 P25025 1/20 0.45
MAPK14 Q16539 1/20 0.45
P2RX1 P51575 1/20 0.41
P2RX3 P56373 1/20 0.41
P2RX4 Q99571 1/20 0.41
P2RX7 Q99572 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
CNR2 P34972 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MITF O75030 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30867643 0.86 HDAC3 (0.46) PPARGCXCR2MAPK14P2RX1P2RX3
SCHEMBL7539315 0.83 WDR5 (0.51) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL3926072 0.81 CXCR2 (0.66) WDR5PPARGPPARALDHACXCR2
SCHEMBL7538596 0.80 WDR5 (0.47) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL28818843 0.78 MAPK14 (0.47) PPARGMAPK14MEN1KMT2AMITF
SCHEMBL30867648 0.77 KDM1A (0.40) PPARGMAPK14CNR2MEN1KMT2A
SCHEMBL27749570 0.77 MAPT (0.52) WDR5P2RX1P2RX3P2RX4P2RX7
SCHEMBL8994662 0.76 MEN1 (0.47) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL28644387 0.76 SCN9A (0.46) PPARGPPARAMAPK14MEN1KMT2A
SCHEMBL10835931 0.76 WDR5 (0.63) WDR5LDHAP2RX1P2RX3P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055144-A Compounds and methods for treating cancer 维瓦斯治疗公司 2026-05-15 CN disclosed
CN-114072207-B Bicyclic compounds 维瓦斯治疗公司 2024-03-29 CN disclosed