SCHEMBL7538596

SCHEMBL7538596

O=Cc1ccc(Oc2c(C(=O)O)ccc3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.47
LDHA P00338 1/20 0.46
CYP1B1 Q16678 2/20 0.44
CYP1A1 P04798 1/20 0.44
MAPT P10636 3/20 0.43
ALDH1A1 P00352 3/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
MITF O75030 2/20 0.41
ABCG2 Q9UNQ0 2/20 0.41
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 3/20 0.41
NPC1 O15118 2/20 0.41
KLF5 Q13887 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7539315 0.84 WDR5 (0.51) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL7536330 0.82 ALDH1A1 (0.45) MAPTALDH1A1KMT2ALMNAPOLB
SCHEMBL30867646 0.80 WDR5 (0.46) WDR5LDHAALDH1A1NR4A1NR4A2
SCHEMBL7182672 0.79 ALDH1A1 (0.46) MAPTALDH1A1KMT2ALMNARAB9A
SCHEMBL8994662 0.77 MEN1 (0.47) WDR5LDHACYP1B1CYP1A1MAPT
SCHEMBL30874079 0.77 WDR5 (0.62) WDR5LDHACYP1B1CYP1A1MAPT
SCHEMBL24815419 0.73 MAPT (0.49) MAPTALDH1A1KMT2ALMNAL3MBTL1
SCHEMBL707315 0.73 CTNNB1 (0.53) MAPTALDH1A1KMT2AMEN1MITF
SCHEMBL30874097 0.73 MAPT (0.49) MAPTALDH1A1KMT2ALMNAL3MBTL1
SCHEMBL10930853 0.72 LDHA (0.54) WDR5LDHACYP1B1CYP1A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 WDR5 852/4885LDHA 1723/4885CYP1B1 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.