Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22559305 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BMCHR1TAAR1PDCD1LG2 | |
| SCHEMBL7859352 | 0.86 | MTNR1A (0.43) | MTNR1AMTNR1BMCHR1CYP1A2CYP3A4 | |
| SCHEMBL1712155 | 0.81 | MTNR1A (0.46) | MTNR1AMTNR1BMCHR1PDCD1LG2CD274 | |
| SCHEMBL1712390 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL1723516 | 0.76 | MTNR1A (0.45) | MTNR1AMTNR1BMCHR1 | |
| SCHEMBL1222885 | 0.75 | BACE1 (0.53) | MTNR1AMTNR1BMCHR1 | |
| SCHEMBL3577364 | 0.75 | MCHR1 (0.49) | MTNR1AMTNR1BMCHR1 | |
| SCHEMBL6208088 | 0.75 | MTNR1A (0.41) | MTNR1AMTNR1BMCHR1 | |
| SCHEMBL1711985 | 0.75 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL4489968 | 0.75 | MTNR1A (0.44) | MTNR1AMTNR1BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072207-B | Bicyclic compounds | 维瓦斯治疗公司 | 2024-03-29 | — | — | CN | disclosed |