Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037994 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL6815364 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL27779619 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL29894839 | 0.83 | CA1 (0.50) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL5702570 | 0.83 | CA1 (0.50) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL29095975 | 0.81 | KDM4E (0.48) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL29798862 | 0.81 | KDM4E (0.48) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL20668222 | 0.81 | KDM4E (0.48) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL4886435 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL5462166 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAL3MBTL1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598917-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | Amgen Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| CN-119431458-A | Tungsten-oxygen complex, preparation method and application thereof in olefin oxidative cleavage and C-H bond oxidation | 江苏科技大学 | 2025-02-14 | — | — | CN | disclosed |
| WO-2024076674-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |