Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 8/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.58 |
| ▸ | CCR5 | P51681 | 3/20 | 0.58 |
| ▸ | CCR8 | P51685 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867783 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1LMNATP53KDM4E | |
| SCHEMBL7037994 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1LMNATP53KDM4E | |
| SCHEMBL8526333 | 0.84 | CCR1 (0.55) | SMN1; SMN2L3MBTL1LMNATP53KDM4E | |
| SCHEMBL16774675 | 0.82 | TGFBR1 (0.46) | SMN1; SMN2LMNATP53KDM4EALOX15 | |
| SCHEMBL5681545 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1LMNATP53KDM4E | |
| SCHEMBL3131063 | 0.78 | PDGFRB (0.43) | SMN1; SMN2L3MBTL1LMNAKDM4EHTT | |
| SCHEMBL5462166 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1LMNATP53KDM4E | |
| SCHEMBL5702570 | 0.76 | CA1 (0.50) | SMN1; SMN2LMNATP53KDM4ETDP1 | |
| SCHEMBL29894839 | 0.76 | CA1 (0.50) | SMN1; SMN2LMNATP53KDM4ETDP1 | |
| Terpyridine SCHEMBL30610403 | 0.76 | KDM4E (0.90) | SMN1; SMN2L3MBTL1LMNATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119637-B8 | SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | THERASENSE INC (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1119637-A1 | SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | Therasense, Inc. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020626-A1 | SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | THERASENSE, INC. (US) | 2000-04-13 | — | — | WO | disclosed |