Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31648987 | 0.98 | PSMB5 (0.40) | PDGFRBPDGFRAPSMB5KDM4EGLA | |
| SCHEMBL16908273 | 0.92 | KDM4E (0.38) | KDM4EHRH1HRH4HRH3MAPK1 | |
| SCHEMBL30868089 | 0.78 | HRH4 (0.32) | HRH1HRH4HRH3MAPK1 | |
| SCHEMBL30868058 | 0.74 | BACE1 (0.37) | HRH4BACE1TDO2CYP11B2 | |
| SCHEMBL20000562 | 0.74 | PDGFRB (0.44) | PDGFRBPDGFRAFEN1ALOX5AP | |
| SCHEMBL30868243 | 0.74 | TNKS (0.47) | PDGFRBPDGFRAPSMB5HTTHRH2 | |
| SCHEMBL30868550 | 0.73 | KDM4E (0.44) | PDGFRBPDGFRAPSMB5KDM4EGLA | |
| SCHEMBL21712544 | 0.73 | KDM4E (0.38) | PDGFRBPDGFRAPSMB5KDM4EHRH2 | |
| SCHEMBL17156238 | 0.72 | KDM4E (0.40) | PDGFRBPDGFRAPSMB5KDM4E | |
| SCHEMBL18722123 | 0.71 | L3MBTL1 (0.47) | PDGFRBPDGFRAPSMB5KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025131978-A1 | DRUG-LINKER REAGENTS FOR CONJUGATION | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |