Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | FEN1 | P39748 | 3/20 | 0.32 |
| ▸ | MET | P08581 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83983 | 1.00 | NOS3 (0.34) | NOS3NOS1NOS2P2RX3P2RX2 | |
| SCHEMBL30868421 | 0.81 | DEGS1 (0.31) | NOS3NOS1NOS2VRK1CPB2 | |
| SCHEMBL30868338 | 0.81 | USP2 (0.39) | NOS3NOS1NOS2VRK1CPB2 | |
| SCHEMBL30144075 | 0.78 | EIF4A3 (0.33) | EIF4A3 | |
| SCHEMBL8030847 | 0.78 | EIF4A3 (0.33) | EIF4A3 | |
| SCHEMBL15471948 | 0.78 | HTT (0.42) | NOS3NOS1NOS2P2RX3P2RX2 | |
| SCHEMBL14225108 | 0.77 | S1PR1 (0.33) | EIF4A3 | |
| SCHEMBL22076927 | 0.77 | GABRA1 (0.38) | VRK1HTTALDH1A1GAAALOX12 | |
| SCHEMBL29910000 | 0.77 | GABRA1 (0.38) | NOS3NOS1NOS2P2RX3P2RX2 | |
| SCHEMBL84407 | 0.77 | NOS3 (0.56) | NOS3NOS1NOS2P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |