Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28000213 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1TDP1KCNH2SMN1; SMN2 | |
| SCHEMBL4158319 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1TDP1KCNH2SMN1; SMN2 | |
| SCHEMBL21275803 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1TDP1KCNH2SMN1; SMN2 | |
| SCHEMBL119201 | 0.69 | ALDH1A1 (0.43) | KDM4EALDH1A1ALOX5APFEN1SMN1; SMN2 | |
| Bromide SCHEMBL6033070 | 0.68 | ALDH1A1 (0.42) | KDM4EALDH1A1ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16813070 | 0.68 | KDM4E (0.63) | KDM4EALDH1A1TDP1KCNH2ALOX5AP | |
| SCHEMBL3627129 | 0.68 | ALDH1A1 (0.54) | KDM4EALDH1A1TDP1KCNH2SMN1; SMN2 | |
| SCHEMBL15201429 | 0.68 | MAOA (0.40) | ALOX5APFEN1VRK1MAPTTSHR | |
| SCHEMBL10281060 | 0.68 | KDM4E (0.36) | KDM4EALDH1A1TDP1KCNH2SMN1; SMN2 | |
| SCHEMBL15688569 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |