Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753424 | 1.00 | PDK1 (0.53) | PDK1KAT2BSNCAALDH1A1MAPT | |
| SCHEMBL30869160 | 1.00 | PDK1 (0.53) | PDK1KAT2BSNCAALDH1A1MAPT | |
| SCHEMBL12737465 | 0.91 | KAT2B (0.48) | PDK1KAT2BSNCAALDH1A1MAPT | |
| SCHEMBL13520160 | 0.89 | ALDH1A1 (0.53) | PDK1KAT2BSNCAALDH1A1MAPT | |
| SCHEMBL30242495 | 0.88 | KAT2B (0.46) | PDK1KAT2BSNCAALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL5983186 | 0.88 | TSHR (0.47) | PDK1KAT2BSNCAALDH1A1MAPT | |
| SCHEMBL9516505 | 0.88 | KAT2B (0.46) | PDK1KAT2BSNCAALDH1A1MAPT | |
| SCHEMBL1670611 | 0.87 | PDK1 (0.53) | PDK1KAT2BSNCAALDH1A1MAPT | |
| SCHEMBL10959235 | 0.86 | TSHR (0.55) | KAT2BALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL13344089 | 0.84 | KAT2B (0.48) | PDK1KAT2BSNCAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924177-A | Preparation method of pazopanib intermediate 2, 3-dimethyl-6-amino-2H-indazole and analogues thereof | 南京杰运医药科技有限公司 | 2024-04-26 | — | — | CN | disclosed |