SCHEMBL30869600

SCHEMBL30869600

Brc1ccc2c(c1)Oc1cc(Br)cnc1N2CCOCCN1CC2COCC(C2)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
PIM1 P11309 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869659 0.91 PIM1 (0.32) PIM1
SCHEMBL30869482 0.91 PIM1 (0.32) PIM1
SCHEMBL30869680 0.91 TSHR (0.32) TSHR
SCHEMBL30869904 0.90 PIM1 (0.32) PIM1
SCHEMBL30869449 0.89 TSHR (0.35) TSHRPIM1
SCHEMBL30869788 0.87
SCHEMBL30869621 0.83 TSHR (0.50) TSHRPIM1
SCHEMBL30869592 0.83 PRMT5 (0.31)
SCHEMBL30869533 0.83
SCHEMBL30869534 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed