SCHEMBL30869592

SCHEMBL30869592

OC(CN1CC2COCC(C2)C1)CN1c2ccc(Br)cc2Oc2cc(Br)cnc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869489 0.91
SCHEMBL30869404 0.89 KMT2A (0.33) PRMT5WDR77MAPK1
SCHEMBL30869825 0.88
SCHEMBL30869482 0.85 PIM1 (0.32)
SCHEMBL30869659 0.85 PIM1 (0.32)
SCHEMBL30869904 0.85 PIM1 (0.32)
SCHEMBL30869640 0.83 MAPK1 (0.47) MAPK1
SCHEMBL30869600 0.83 TSHR (0.32)
SCHEMBL30869613 0.81 MAPK1 (0.32) PRMT5WDR77MAPK1
SCHEMBL30869533 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed