SCHEMBL30869449

SCHEMBL30869449

Brc1ccc2c(c1)Oc1cc(Br)ccc1N2CCOCCN1CC2COCC(C2)C1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
PIM1 P11309 3/20 0.33
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869381 0.90 PIM1 (0.34) PIM1
SCHEMBL30869398 0.90 SMPD1 (0.35) PIM1
SCHEMBL30869423 0.89 PIM1 (0.40) PIM1
SCHEMBL30869600 0.89 TSHR (0.32) TSHRPIM1
SCHEMBL30869517 0.88 PIM1 (0.34) PIM1
SCHEMBL30869680 0.80 TSHR (0.32) TSHR
SCHEMBL30869458 0.80 TSHR (0.56) TSHRPIM1KDM4EALDH1A1SMN1; SMN2
SCHEMBL30869482 0.79 PIM1 (0.32) PIM1
SCHEMBL30869659 0.79 PIM1 (0.32) PIM1
SCHEMBL30869404 0.77 KMT2A (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 TSHR 2846/4885PIM1 4177/4885KDM4E 2562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.