SCHEMBL30869640

SCHEMBL30869640

OC(CN1CCOCC1)CN1c2ccc(Br)cc2Oc2cc(Br)cnc21

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.47
TSHR P16473 4/20 0.45
USP2 O75604 2/20 0.45
KMT2A Q03164 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.38
ATM Q13315 1/20 0.37
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869590 0.87 PIM1 (0.45) MAPK1TSHRKMT2AMEN1
SCHEMBL30869613 0.85 MAPK1 (0.32) MAPK1
SCHEMBL30869403 0.84 EGFR (0.43) TSHRSMN1; SMN2
SCHEMBL30869652 0.84 EGFR (0.41) TSHRSMN1; SMN2
SCHEMBL30869592 0.83 PRMT5 (0.31) MAPK1
SCHEMBL30869621 0.81 TSHR (0.50) TSHRSMN1; SMN2
SCHEMBL30869759 0.76 HTT (0.35)
SCHEMBL30869767 0.76 TSHR (0.47) TSHRKMT2ASMN1; SMN2GAAMEN1
SCHEMBL30869389 0.75 AHR (0.34) MAPK1TSHRKMT2AMEN1
SCHEMBL30869597 0.73 PIM1 (0.50) MAPK1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed