SCHEMBL30869712

SCHEMBL30869712

Brc1ccc2c(c1)Oc1cc(Br)ccc1N2CCN1CC2(COC2)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.41
AHR P35869 3/20 0.35
HTR1A P08908 1/20 0.33
ADRA1B P35368 1/20 0.33
MEN1 O00255 1/20 0.33
TDP2 O95551 1/20 0.33
CFTR P13569 1/20 0.33
CASP6 P55212 1/20 0.33
KMT2A Q03164 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
GOPC Q9HD26 1/20 0.33
L3MBTL3 Q96JM7 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CNR1 P21554 1/20 0.32
PKM P14618 1/20 0.32
DRD2 P14416 1/20 0.30
HTR2A P28223 1/20 0.30
HTR7 P34969 1/20 0.30
HTR6 P50406 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869631 0.92 PIM1 (0.35) PIM1AHRL3MBTL3L3MBTL1PKM
SCHEMBL30869647 0.92 PIM1 (0.35) PIM1AHRL3MBTL3L3MBTL1PKM
SCHEMBL30869781 0.91 PIM1 (0.35) PIM1AHRL3MBTL3L3MBTL1PKM
SCHEMBL30869465 0.89 TSHR (0.36) PIM1AHRMEN1KMT2A
SCHEMBL30869733 0.87 PIM1 (0.40) PIM1AHRHTR1AADRA1BMEN1
SCHEMBL30869731 0.81 MAPK1 (0.34) AHRMEN1KMT2AMAPT
SCHEMBL30869461 0.81 PIM1 (0.33) PIM1
SCHEMBL30869597 0.80 PIM1 (0.50) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869541 0.80 PIM1 (0.34) PIM1AHRDRD2HTR2AHTR7
SCHEMBL30869539 0.80 PIM1 (0.34) PIM1AHRDRD2HTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed