SCHEMBL30869731

SCHEMBL30869731

OC(CN1CC2(COC2)C1)CN1c2ccc(Br)cc2Oc2cc(Br)ccc21

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
BAX Q07812 1/20 0.34
PRMT5 O14744 9/20 0.33
WDR77 Q9BQA1 6/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
MEN1 O00255 1/20 0.32
RAD52 P43351 1/20 0.32
KMT2A Q03164 1/20 0.32
USP2 O75604 1/20 0.32
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
AHR P35869 1/20 0.31
CARM1 Q86X55 2/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869613 0.89 MAPK1 (0.32) MAPK1PRMT5WDR77
SCHEMBL14808960 0.83 PRMT5 (0.41) PRMT5WDR77TP53MAPTMEN1
SCHEMBL30869712 0.81 PIM1 (0.41) MAPTMEN1KMT2AAHR
SCHEMBL30869631 0.79 PIM1 (0.35) AHR
SCHEMBL30869647 0.79 PIM1 (0.35) AHR
SCHEMBL30869781 0.78 PIM1 (0.35) AHR
SCHEMBL30869404 0.77 KMT2A (0.33) MAPK1BAXPRMT5WDR77TP53
SCHEMBL30869465 0.76 TSHR (0.36) MEN1KMT2ATSHRAHR
SCHEMBL30869833 0.76 PRMT5 (0.39) MAPK1PRMT5WDR77
SCHEMBL14823908 0.74 RAD52 (0.35) PRMT5WDR77RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 MAPK1 715/4885BAX 1339/4885PRMT5 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.