SCHEMBL30869733

SCHEMBL30869733

C[C@@]12COC[C@]1(C)CN(CCN1c3ccc(Br)cc3Oc3cc(Br)ccc31)C2

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.40
MEN1 O00255 1/20 0.34
TDP2 O95551 1/20 0.34
CFTR P13569 1/20 0.34
CASP6 P55212 1/20 0.34
KMT2A Q03164 1/20 0.34
HKDC1 Q2TB90 1/20 0.34
GOPC Q9HD26 1/20 0.34
AHR P35869 3/20 0.33
DRD2 P14416 1/20 0.32
HTR2A P28223 1/20 0.32
HTR7 P34969 1/20 0.32
HTR6 P50406 1/20 0.32
CNR1 P21554 1/20 0.30
PKM P14618 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA1B P35368 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869541 0.93 PIM1 (0.34) PIM1AHRDRD2HTR2AHTR7
SCHEMBL30869539 0.93 PIM1 (0.34) PIM1AHRDRD2HTR2AHTR7
SCHEMBL30869712 0.87 PIM1 (0.41) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869566 0.81 PIM1 (0.32) PIM1
SCHEMBL30869647 0.80 PIM1 (0.35) PIM1AHRPKM
SCHEMBL30869631 0.80 PIM1 (0.35) PIM1AHRPKM
SCHEMBL30869781 0.79 PIM1 (0.35) PIM1AHRPKM
SCHEMBL30869494 0.78 CUL4A (0.33) MEN1TDP2CFTRCASP6KMT2A
SCHEMBL30869597 0.78 PIM1 (0.50) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869465 0.77 TSHR (0.36) PIM1MEN1KMT2AAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 PIM1 4177/4885MEN1 1625/4885TDP2 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.