SCHEMBL30869720

SCHEMBL30869720

CN1CCN(CCN2c3ccc(Br)cc3Sc3cc(Br)ccc32)CC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 12/20 0.64
DRD2 P14416 4/20 0.53
HTR2A P28223 4/20 0.53
HTR7 P34969 3/20 0.53
HTR6 P50406 2/20 0.53
LMNA P02545 3/20 0.47
TP53 P04637 3/20 0.47
CYP3A4 P08684 3/20 0.47
HTR1A P08908 3/20 0.47
ADRA2A P08913 3/20 0.47
ADORA3 P0DMS8 3/20 0.47
MAPT P10636 3/20 0.47
CHRM1 P11229 3/20 0.47
ADRA2C P18825 3/20 0.47
DRD1 P21728 3/20 0.47
SLC6A2 P23975 3/20 0.47
MAPK1 P28482 3/20 0.47
SLC6A4 P31645 3/20 0.47
ADRA1A P35348 3/20 0.47
HRH1 P35367 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869556 0.85 KDM1A (0.64) KDM1ADRD2HTR2AHTR7HTR6
SCHEMBL13393393 0.85 KDM1A (0.77) KDM1ADRD2HTR2AHTR6LMNA
SCHEMBL12073897 0.78 DRD2 (0.53) KDM1ADRD2HTR2AHTR7HTR6
SCHEMBL13393374 0.76 KDM1A (0.78) KDM1ADRD2HTR2AHTR6LMNA
SCHEMBL29947109 0.76 DRD2 (0.51) KDM1ADRD2HTR2AHTR7HTR6
SCHEMBL27236434 0.76 DRD2 (0.51) KDM1ADRD2HTR2AHTR7HTR6
SCHEMBL32682874 0.74 DRD2 (0.50) KDM1ADRD2HTR2AHTR7HTR6
SCHEMBL15237156 0.74 DRD2 (0.49) KDM1ADRD2HTR2AHTR7HTR6
Bromide SCHEMBL2590637 0.74 DRD2 (0.50) KDM1ADRD2HTR2AHTR7HTR6
SCHEMBL19897162 0.74 DRD2 (0.53) KDM1ADRD2HTR2AHTR7HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed