SCHEMBL30869737

SCHEMBL30869737

Brc1ccc2c(c1)Oc1cc(Br)ccc1N2CCCCCN1CCOCC1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.51
KDM4E B2RXH2 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.44
PIM1 P11309 1/20 0.44
TSHR P16473 3/20 0.43
EGFR P00533 2/20 0.42
MEN1 O00255 1/20 0.42
TDP2 O95551 1/20 0.42
CFTR P13569 1/20 0.42
CASP6 P55212 1/20 0.42
KMT2A Q03164 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
GOPC Q9HD26 1/20 0.42
LSS P48449 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869597 0.92 PIM1 (0.50) KDM1ALMNAPIM1TSHRMEN1
SCHEMBL30869458 0.87 TSHR (0.56) KDM4ESMN1; SMN2LMNAPIM1TSHR
SCHEMBL30869652 0.86 EGFR (0.41) KDM1AKDM4ESMN1; SMN2LMNAPIM1
SCHEMBL30869403 0.83 EGFR (0.43) KDM1AKDM4ESMN1; SMN2LMNAPIM1
SCHEMBL30869781 0.81 PIM1 (0.35) KDM1APIM1EGFR
SCHEMBL30869593 0.80 AHR (0.41) PIM1TSHRMEN1KMT2A
SCHEMBL30869647 0.79 PIM1 (0.35) KDM1APIM1EGFR
SCHEMBL30869517 0.79 PIM1 (0.34) KDM1APIM1
SCHEMBL30869590 0.79 PIM1 (0.45) LMNAPIM1TSHREGFRMEN1
SCHEMBL3023529 0.79 CNR1 (0.42) KDM4ESMN1; SMN2LMNAPIM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed