SCHEMBL30869458

SCHEMBL30869458

Brc1ccc2c(c1)Oc1cc(Br)ccc1N2CCOCCN1CCOCC1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
ALDH1A1 P00352 2/20 0.45
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
PIM1 P11309 1/20 0.42
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
TDP2 O95551 1/20 0.40
CFTR P13569 1/20 0.40
CASP6 P55212 1/20 0.40
KMT2A Q03164 1/20 0.40
HKDC1 Q2TB90 1/20 0.40
GOPC Q9HD26 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869597 0.89 PIM1 (0.50) TSHRALDH1A1MAPTHTTPIM1
SCHEMBL30869621 0.88 TSHR (0.50) TSHRALDH1A1MAPTHTTPIM1
SCHEMBL30869737 0.87 KDM1A (0.51) TSHRPIM1KDM4ESMN1; SMN2LMNA
SCHEMBL30869465 0.81 TSHR (0.36) TSHRPIM1MEN1KMT2A
SCHEMBL32682896 0.81 AHR (0.39) TSHRPIM1
SCHEMBL30869449 0.80 TSHR (0.35) TSHRALDH1A1PIM1KDM4ESMN1; SMN2
SCHEMBL30869487 0.78 TSHR (0.51) TSHRALDH1A1MAPTHTTKDM4E
SCHEMBL30869590 0.77 PIM1 (0.45) TSHRALDH1A1MAPTHTTPIM1
SCHEMBL30869652 0.76 EGFR (0.41) TSHRALDH1A1PIM1KDM4ESMN1; SMN2
SCHEMBL30869403 0.76 EGFR (0.43) TSHRPIM1KDM4ESMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 TSHR 2846/4885ALDH1A1 4860/4885MAPT 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.