SCHEMBL30869778

SCHEMBL30869778

Cc1cc2c(cc1Br)Oc1cc(Br)cnc1N2CCCCN1C[C@H]2C[C@@H]1CO2

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869422 1.00 KIF11 (0.32) KIF11
SCHEMBL30869373 0.99 KIF11 (0.31) KIF11
SCHEMBL30869565 0.99 KIF11 (0.31) KIF11
SCHEMBL30869579 0.91 ESR1 (0.32)
SCHEMBL30869651 0.91 ESR1 (0.32)
SCHEMBL30869601 0.89 ESR1 (0.33) KIF11
SCHEMBL30869401 0.89 ESR1 (0.33) KIF11
SCHEMBL30869444 0.88 ESR1 (0.33) KIF11
SCHEMBL30869687 0.88 ESR1 (0.33) KIF11
SCHEMBL30869520 0.87 PIM1 (0.33) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed