Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 13/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869395 | 1.00 | ALDH1A1 (0.47) | ALDH1A1DRD2CALCRLCHRM1LMNA | |
| SCHEMBL22869588 | 0.88 | ALDH1A1 (0.47) | ALDH1A1DRD2CALCRLCHRM1LMNA | |
| SCHEMBL30870214 | 0.88 | ALDH1A1 (0.47) | ALDH1A1DRD2CALCRLCHRM1LMNA | |
| SCHEMBL30870368 | 0.86 | ALDH1A1 (0.45) | ALDH1A1DRD2CALCRLCHRM1LMNA | |
| SCHEMBL22869840 | 0.86 | ALDH1A1 (0.45) | ALDH1A1DRD2CALCRLCHRM1LMNA | |
| SCHEMBL27207701 | 0.85 | ALDH1A1 (0.44) | ALDH1A1DRD2CALCRLCHRM1LMNA | |
| SCHEMBL22869509 | 0.85 | HSD11B1 (0.56) | ALDH1A1DRD2CALCRLCHRM1 | |
| SCHEMBL30870292 | 0.85 | HSD11B1 (0.56) | ALDH1A1DRD2CALCRLCHRM1 | |
| SCHEMBL22869548 | 0.83 | ALDH1A1 (0.52) | ALDH1A1DRD2CALCRLCHRM1LMNA | |
| SCHEMBL30870144 | 0.83 | ALDH1A1 (0.52) | ALDH1A1DRD2CALCRLCHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | claimed |