Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869849 | 1.00 | HSD11B1 (0.65) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL30870193 | 0.94 | HSD11B1 (0.74) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL22869508 | 0.94 | HSD11B1 (0.74) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL22869487 | 0.93 | HSD11B1 (0.55) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL30870191 | 0.93 | HSD11B1 (0.55) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL22869654 | 0.92 | HSD11B1 (0.66) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL30870358 | 0.92 | HSD11B1 (0.66) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL30870237 | 0.90 | DRD2 (0.57) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL22869580 | 0.90 | HSD11B1 (0.53) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 | |
| SCHEMBL22869401 | 0.90 | DRD2 (0.57) | HSD11B1DRD2ALDH1A1CHRM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | claimed |
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |