SCHEMBL3087030

SCHEMBL3087030

CC(Cc1ccccc1)OC(=O)c1ccccc1NC(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
KDM4E B2RXH2 5/20 0.49
LMNA P02545 3/20 0.49
ALDH1A1 P00352 6/20 0.48
HPGD P15428 3/20 0.48
CYP2C19 P33261 2/20 0.48
HTT P42858 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
MAPT P10636 1/20 0.48
CYP2C9 P11712 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CYP1A2 P05177 1/20 0.48
CTSL P07711 1/20 0.47
CTSB P07858 1/20 0.47
CTSS P25774 1/20 0.47
CTSK P43235 1/20 0.47
CTRB1 P17538 2/20 0.47
CASP3 P42574 1/20 0.46
RAF1 P04049 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10874779 0.84 NPC1 (0.68) NPC1RAB9AKDM4ELMNAALDH1A1
SCHEMBL20357950 0.80 ALDH1A1 (0.55) NPC1RAB9AALDH1A1CYP1A2CTSL
SCHEMBL2233522 0.79 NPC1 (0.69) NPC1RAB9AKDM4ELMNAALDH1A1
SCHEMBL6190439 0.76 NPC1 (0.66) NPC1RAB9ALMNAALDH1A1CYP2C19
SCHEMBL5056843 0.76 CYP2C19 (0.60) NPC1RAB9AKDM4ELMNAALDH1A1
SCHEMBL20357953 0.76 ALDH1A1 (0.62) NPC1RAB9AALDH1A1CYP1A2CTSL
SCHEMBL27567788 0.76 CYP1A2 (0.63) NPC1RAB9AKDM4ELMNAALDH1A1
SCHEMBL10192674 0.75 NPC1 (0.64) NPC1RAB9AKDM4EALDH1A1CYP2C19
SCHEMBL5055467 0.75 NPC1 (0.57) NPC1RAB9AKDM4ELMNAALDH1A1
SCHEMBL5853278 0.75 NPC1 (1.00) NPC1RAB9AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795166-B2 Functional group-selective hydrogenation catalyst and functional group-selective hydrogenation method N.E. CHEMCAT CORPORATION (JP) 2010-09-14 US disclosed
US-20070155617-A1 FUNCTIONAL GROUP-SELECTIVE HYDROGENATION CATALYST AND FUNCTIONAL GROUP-SELECTIVE HYDROGENATION METHOD N. E. CHEMCAT CORPORATION (JP) 2007-07-05 US disclosed