SCHEMBL30870404

SCHEMBL30870404

O=C1Nc2ccccc2C1(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGAM O43451 10/20 1.00
GAA P10253 10/20 1.00
SI P14410 10/20 1.00
MGAM2 Q2M2H8 10/20 1.00
HTR1A P08908 1/20 0.70
HTR2A P28223 1/20 0.70
HTR7 P34969 1/20 0.70
HTR6 P50406 1/20 0.70
LMNA P02545 1/20 0.53
PIM1 P11309 1/20 0.49
CHRM2 P08172 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
KCNH2 Q12809 1/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20550167 1.00 MGAM (1.00) MGAMGAASIMGAM2HTR1A
SCHEMBL29628076 0.81 PIM1 (0.71) MGAMGAASIMGAM2HTR1A
SCHEMBL5435863 0.81 PIM1 (0.71) MGAMGAASIMGAM2HTR1A
SCHEMBL11897032 0.81 MGAM (0.68) MGAMGAASIMGAM2HTR1A
SCHEMBL25340217 0.76 LMNA (0.76) MGAMGAASIMGAM2LMNA
SCHEMBL28453250 0.76 MGAM (0.60) MGAMGAASIMGAM2HTR1A
SCHEMBL21307359 0.74 MGAM (0.58) MGAMGAASIMGAM2HTR1A
SCHEMBL31347809 0.74 MGAM (0.58) MGAMGAASIMGAM2HTR1A
SCHEMBL11897129 0.73 GAA (0.56) MGAMGAASIMGAM2HTR1A
SCHEMBL11897128 0.71 GAA (0.54) MGAMGAASIMGAM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119506179-A Escherichia coli recombinant engineering bacteria and application thereof 河南省商业科学研究所有限责任公司 2025-02-25 CN disclosed
CN-117700407-A 3, 3-disubstituted indol-2-one compound and preparation method and application thereof 五邑大学 2024-03-15 CN disclosed