Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503434 | 1.00 | KDM4E (0.47) | KDM4EMAPTTHRBHCAR1CCR5 | |
| SCHEMBL23253207 | 0.94 | HSD11B1 (0.49) | KDM4EMAPTTHRBHCAR1PIK3CA | |
| SCHEMBL23253206 | 0.94 | HSD11B1 (0.49) | KDM4EMAPTTHRBHCAR1PIK3CA | |
| SCHEMBL30677777 | 0.91 | KDM4E (0.45) | KDM4EMAPTTHRBHCAR1PIK3CA | |
| SCHEMBL2636724 | 0.83 | HSD11B1 (0.59) | KDM4EMAPTTHRBHCAR1CCR5 | |
| SCHEMBL2636722 | 0.83 | HSD11B1 (0.59) | KDM4EMAPTTHRBHCAR1CCR5 | |
| SCHEMBL2248725 | 0.82 | CCR5 (0.52) | HCAR1CCR5CHRM2CHRM4CHRM5 | |
| SCHEMBL29198147 | 0.82 | CHRM1 (0.53) | CCR5CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23253093 | 0.82 | HSD11B1 (0.47) | KDM4EMAPTTHRBHCAR1PIK3CA | |
| SCHEMBL23253094 | 0.82 | HSD11B1 (0.47) | KDM4EMAPTTHRBHCAR1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |