SCHEMBL308706

SCHEMBL308706

c1ccc([SiH](O[SiH](c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.35
LTA4H P09960 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CA4 P22748 2/20 0.32
DAO P14920 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30
TRPV6 Q9H1D0 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
CA12 O43570 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30
CA14 Q9ULX7 1/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16178636 0.97 TSHR (0.33) TSHRLTA4HALDH1A1CA4DAO
SCHEMBL13822318 0.88 LTA4H (0.32) TSHRLTA4HALDH1A1
SCHEMBL3874474 0.85 LTA4H (0.30) TSHRLTA4H
SCHEMBL3294404 0.84 ACHE (0.46) TSHRALDH1A1TDP1LMNAALOX12
SCHEMBL1147930 0.83 CA4 (0.32) TSHRCA4LMNAALOX12ACHE
SCHEMBL3868214 0.83
SCHEMBL3878566 0.83
SCHEMBL3874053 0.83
SCHEMBL28758122 0.81 CA4 (0.31) CA4
SCHEMBL3295781 0.81 CA4 (0.54) LTA4HALDH1A1CA4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384917-B1 Physical characteristics of polysilylether polymers in additive manufacturing of energetic materials THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2025-08-12 US claimed
WO-2022154598-A1 PLATE FOR PRODUCING STEM CELL SPHEROID AND METHOD FOR PRODUCING STEM CELL SPHEROID BY USING SAME 한국과학기술원 2022-07-21 WO claimed
US-20060270787-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes VERSUM MATERIALS US, LLC 2006-11-30 US claimed
US-7129311-B2 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-10-31 US claimed
US-20060159861-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-07-20 US claimed
EP-1573086-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES Arch Specialty Chemicals, Inc. (US) 2005-09-14 EP claimed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US claimed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO claimed
EP-0610818-B1 Method for preparation of a silicone resin DOW CORNING TORAY SILICONE (JP) 1997-06-11 EP claimed
EP-0610818-A1 Method for preparation of a silicone resin Dow Corning Toray Silicone Company, Limited (JP) 1994-08-17 EP claimed
US-5338817-A Method for the preparation of a silicone resin DOW CORNING TORAY SILICONE CO., LTD. (JP) 1994-08-16 US claimed
EP-4700090-A1 PLATINUM-PHOSPHITE COMPLEX-CONTAINING HYDROSILYLATION CATALYST, METHOD FOR PRODUCING SAID PLATINUM-PHOSPHITE COMPLEX-CONTAINING HYDROSILYLATION CATALYST, AND CURABLE ORGANOPOLYSILOXANE COMPOSITION CONTAINING SAID CATALYST SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-02-25 EP disclosed
EP-4688260-A1 COMPOSITION AND METHOD OF PREPARING HYDROSILYLATION REACTION PRODUCT Dow Silicones Corporation (US) 2026-02-11 EP disclosed
EP-4688259-A1 ENCAPSULATED CATALYST, METHOD OF PREPARATION, COMPOSITION AND METHODS INVOLVING HYDROSILYLATION Dow Silicones Corporation (US) 2026-02-11 EP disclosed
US-12497511-B2 Crosslinkable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2025-12-16 US disclosed
US-5416233-A Preparation of vinylsilane-benzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1995-05-16 US disclosed
EP-0610818-A1 Method for preparation of a silicone resin Dow Corning Toray Silicone Company, Limited (JP) 1994-08-17 EP disclosed
US-5338817-A Method for the preparation of a silicone resin DOW CORNING TORAY SILICONE CO., LTD. (JP) 1994-08-16 US disclosed
US-4315088-A COORDINATION CATALYST MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1982-02-09 US disclosed
US-4309557-A Process for the preparation of alkyl and aryl substituted oligosiloxanes suitable for use as diffusion pump oils NUSIL RESEARCH (US) 1982-01-05 US disclosed