Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 9/20 | 0.34 |
| ▸ | CBL | P22681 | 8/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30521047 | 0.85 | CBL (0.34) | CBLBCBL | |
| SCHEMBL25414185 | 0.85 | CBLB (0.33) | CBLBCBLHSD11B1 | |
| SCHEMBL30872146 | 0.81 | CBLB (0.48) | CBLBCBL | |
| SCHEMBL31459013 | 0.81 | CBLB (0.34) | CBLBCBL | |
| SCHEMBL30184943 | 0.81 | CBLB (0.37) | CBLBCBLHSD11B1 | |
| SCHEMBL31274881 | 0.78 | CBLB (0.35) | CBLBCBLHSD11B1 | |
| SCHEMBL31275333 | 0.78 | CBLB (0.35) | CBLB | |
| SCHEMBL26338174 | 0.77 | CBLB (0.40) | CBLBCBL | |
| SCHEMBL31251303 | 0.76 | HSD11B1 (0.31) | CBLBCBLHSD11B1 | |
| SCHEMBL31459060 | 0.76 | CBL (0.32) | CBLBCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |