SCHEMBL30872146

SCHEMBL30872146

CC1CC(c2ccnc(Cl)c2)(c2nncn2C)C1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.48
▸ CBL P22681 18/20 0.48
▸ CBLC Q9ULV8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30521089 0.85 CBLB (0.48) CBLBCBLCBLC
SCHEMBL30521554 0.85 CBLB (0.48) CBLBCBLCBLC
SCHEMBL25413018 0.84 CBLB (0.48) CBLBCBLCBLC
SCHEMBL25413016 0.84 CBLB (0.48) CBLBCBLCBLC
SCHEMBL30872125 0.81 CBLB (0.34) CBLBCBL
SCHEMBL30184956 0.81 CBLB (0.48) CBLBCBLCBLC
SCHEMBL31459096 0.81 CBLB (0.46) CBLBCBL
SCHEMBL30184955 0.81 CBLB (0.57) CBLBCBLCBLC
SCHEMBL30184959 0.80 CBLB (0.52) CBLBCBLCBLC
SCHEMBL30184958 0.80 CBLB (0.52) CBLBCBLCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117940404-A Tricyclic compounds as Cbl-b inhibitors 海南先声再明医药股份有限公司 2024-04-26 — — CN disclosed
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