Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039283 | 0.79 | CYP3A4 (0.43) | SSTR3THRBSMN1; SMN2OPRL1OPRM1 | |
| Bromide SCHEMBL11037477 | 0.78 | CYP3A4 (0.42) | SSTR3THRBSMN1; SMN2OPRL1OPRM1 | |
| SCHEMBL19510352 | 0.77 | CYP2C19 (0.47) | TAAR1LMNASIGMAR1SMN1; SMN2KDM1A | |
| SCHEMBL27800697 | 0.75 | CYP3A4 (0.43) | SSTR3THRBOPRL1OPRM1 | |
| SCHEMBL27893441 | 0.74 | KDM4E (0.42) | SSTR3THRBOPRL1SLC6A4 | |
| SCHEMBL20819627 | 0.72 | SLC6A2 (0.43) | SLC6A3SLC6A2DRD3SLC6A4 | |
| SCHEMBL20819639 | 0.72 | SLC6A2 (0.43) | SLC6A3SLC6A2DRD3SLC6A4 | |
| SCHEMBL30009921 | 0.71 | TAAR1 (0.66) | TAAR1CARM1PRMT6SCN8A | |
| SCHEMBL159689 | 0.71 | TAAR1 (0.66) | TAAR1CARM1PRMT6SCN8A | |
| SCHEMBL27890446 | 0.71 | CYP3A4 (0.46) | THRBSIGMAR1SMN1; SMN2OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |