SCHEMBL159689

SCHEMBL159689

CNCc1cccc(F)c1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.66
PRMT6 Q96LA8 8/20 0.53
CARM1 Q86X55 2/20 0.53
KDM4E B2RXH2 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
NOS1 P29475 1/20 0.49
IDO1 P14902 2/20 0.48
AGXT P21549 2/20 0.48
SCN8A Q9UQD0 1/20 0.47
EPHX2 P34913 1/20 0.47
MPO P05164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009921 1.00 TAAR1 (0.66) TAAR1PRMT6CARM1KDM4ECYP3A4
Hydrochloric Acid SCHEMBL31185480 0.98 TAAR1 (0.63) TAAR1PRMT6CARM1KDM4ECYP3A4
Carbamic Acid SCHEMBL156510 0.88 TAAR1 (0.53) TAAR1NOS1
SCHEMBL1697126 0.84 MAPT (0.64) TAAR1PRMT6KDM4ECYP3A4MAPT
SCHEMBL14612436 0.82 TAAR1 (0.54) TAAR1IDO1AGXTSCN8AMPO
Hydrochloric Acid SCHEMBL3273205 0.81 MAPT (0.68) PRMT6KDM4ECYP3A4MAPTNOS1
SCHEMBL6419246 0.80 CYP19A1 (0.47) TAAR1PRMT6KDM4ECYP3A4MAPT
SCHEMBL25588040 0.80 TAAR1 (0.52) TAAR1IDO1AGXTSCN8AMPO
SCHEMBL30753812 0.79 MPO (0.55) TAAR1NOS1IDO1AGXTSCN8A
SCHEMBL2720282 0.79 MPO (0.55) TAAR1NOS1IDO1AGXTSCN8A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2026-01-08 US claimed
US-12427471-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (NC) 2025-09-30 US claimed
CN-119613607-A Preparation method of 193nm photoresist resin 江苏集萃光敏电子材料研究所有限公司 2025-03-14 CN claimed
CN-119118878-A Paeonol carbamate compound, pharmaceutical preparation, preparation method and application 安徽省第二人民医院(安徽医学高等专科学校附属医院、安徽省职业病防治院) 2024-12-13 CN claimed
CN-115785889-B Polyurethane adhesive for single-sided adhesive shoes and preparation method thereof 福建华夏蓝新材料科技有限公司 2024-07-05 CN claimed
US-20230241547-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2023-08-03 US claimed
CN-116283769-A Cyclobutane-pyridine sulfonamide compound 绍兴市上虞区武汉理工大学高等研究院 2023-06-23 CN claimed
CN-115785889-A Polyurethane adhesive for single-sided sizing shoes and preparation method thereof 福建华夏蓝新材料科技有限公司 2023-03-14 CN claimed
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US claimed
US-20230001348-A1 NON-AQUEOUS SOLVENT FOR REMOVING ACIDIC GAS FROM A PROCESS GAS STREAM FOR HIGH PRESSURE APPLICATIONS RESEARCH TRIANGLE INSTITUTE 2023-01-05 US claimed
EP-2006271-A9 SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2009-07-29 EP claimed
US-20090170852-A1 NOVEL PYRAZOLE-BASED HMG CoA REDUCTASE INHIBITORS PFIZER INC. 2009-07-02 US claimed
CN-101410366-A Substituted bicyclic ring derivatives and uses thereof ASAHI KASEI PHARMA CORP (JP) 2009-04-15 CN claimed
US-20090054401-A1 Substituted bicyclic derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2009-02-26 US claimed
EP-2006271-A2 SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2008-12-24 EP claimed
US-20080200454-A1 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S SUNESIS PHARMACEUTICALS, INC. 2008-08-21 US claimed
WO-2008100618-A2 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S SUNESIS PHARMACEUTICALS, INC. (US) 2008-08-21 WO claimed
EP-1819681-A1 7-(2H-PYRAZOL-3-YL)-3,5-DIHYDROXY-HEPTANOIC ACID DERIVATIVES AS HMG CO-A REDUCTASE INHIBITORS FOR THE TREATMENT OF LIPIDEMIA Warner-Lambert Company LLC (US) 2007-08-22 EP claimed
WO-2006056845-A1 7-(2H-PYRAZOL-3-YL)-3, 5-DIHYROXY-HEPTANOIC ACID DERIVATIVES AS HMG CO-A REDUCTASE INHIBITORS FOR THE TREATMENT OF LIPIDEMIA WARNER-LAMBERT COMPANY LLC (US) 2006-06-01 WO claimed
US-20060111422-A1 Novel pyrazole-based HMG CoA reductase inhibitors WARNER-LAMBERT COMPANY LLC 2006-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054401-A1 Substituted bicyclic derivatives and use thereof LTB4R2, LTC4S, LTB4R TAAR1 1127/4885PRMT6 3251/4885CARM1 2378/4885
US-20090170852-A1 NOVEL PYRAZOLE-BASED HMG CoA REDUCTASE INHIBITORS HMGCR, BPHL, CYP46A1 TAAR1 4078/4885PRMT6 3433/4885CARM1 3487/4885
US-20080200454-A1 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S CTSS, CTSK, CTSZ TAAR1 3251/4885PRMT6 3905/4885CARM1 3877/4885
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION NOS2, DUOX2, SMOX TAAR1 660/4885PRMT6 352/4885CARM1 419/4885
US-20060111422-A1 Novel pyrazole-based HMG CoA reductase inhibitors HMGCR, BPHL, CYP46A1 TAAR1 4078/4885PRMT6 3433/4885CARM1 3487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.