Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pidolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAD | P27708 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pidolic Acid SCHEMBL2453346 | 0.98 | CAD (0.43) | CADMEN1KMT2ASMN1; SMN2POLB | |
| Pidolic Acid SCHEMBL223918 | 0.98 | — | — | |
| Pidolic Acid SCHEMBL1239532 | 0.98 | CAD (0.46) | CADMEN1KMT2ASMN1; SMN2POLB | |
| Pidolic Acid SCHEMBL15790 | 0.98 | — | — | |
| Pidolic Acid SCHEMBL7554345 | 0.98 | CAD (0.46) | CADMEN1KMT2ASMN1; SMN2POLB | |
| Pidolic Acid SCHEMBL15791 | 0.98 | — | — | |
| Pidolic Acid SCHEMBL152441 | 0.98 | CAD (0.46) | CADMEN1KMT2ASMN1; SMN2POLB | |
| Pidolic Acid SCHEMBL29479230 | 0.98 | — | — | |
| Pidolic Acid SCHEMBL10937920 | 0.98 | CAD (0.46) | CADMEN1KMT2ASMN1; SMN2POLB | |
| Pidolic Acid SCHEMBL10875923 | 0.95 | CAD (0.44) | CADMEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139436-A1 | LIQUID INFUSED SURFACE-MODIFIED MATERIAL | OMYA INTERNATIONAL AG (CH) | 2026-05-21 | — | — | US | disclosed |
| EP-4506338-B1 | METHOD FOR PREPARING 2-HYDROXY-5-OXOPROLINE | MILLENNIUM ENTPR INC (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4605596-A1 | LIQUID INFUSED SURFACE-MODIFIED MATERIAL | Omya International AG (CH) | 2025-08-27 | — | — | EP | disclosed |
| WO-2025034253-A1 | METHOD FOR PREPARING 2-HYDROXY-5-OXOPROLINE | Millennium Enterprises, Inc. (US) | 2025-02-13 | — | — | WO | disclosed |
| US-20250051274-A1 | METHOD FOR PREPARING 2-HYDROXY-5-OXOPROLINE | Millennium Enterprises, Inc. (US) | 2025-02-13 | — | — | US | disclosed |
| EP-4506338-A1 | METHOD FOR PREPARING 2-HYDROXY-5-OXOPROLINE | Millennium Enterprises, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2024083812-A1 | LIQUID INFUSED SURFACE-MODIFIED MATERIAL | OMYA INTERNATIONAL AG (CH) | 2024-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139436-A1 | LIQUID INFUSED SURFACE-MODIFIED MATERIAL | FGB, ITGB1, ITGB2 | CAD 691/4885MEN1 320/4885KMT2A 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.