Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 13/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23358982 | 1.00 | ATF4 (0.36) | ATF4KCNH2IDO1DPP8DPP9 | |
| SCHEMBL20722141 | 0.82 | ATF4 (0.46) | ATF4KCNH2DPP8DPP9 | |
| SCHEMBL24462271 | 0.81 | ATF4 (0.43) | ATF4KCNH2PDK2 | |
| SCHEMBL30873692 | 0.76 | ATF4 (0.43) | ATF4KCNH2 | |
| SCHEMBL20734206 | 0.76 | ATF4 (0.56) | ATF4KCNH2 | |
| SCHEMBL23358921 | 0.76 | ATF4 (0.56) | ATF4KCNH2 | |
| Trifluoroacetic Acid SCHEMBL23359012 | 0.74 | CYP11B2 (0.35) | CYP11B2PDK2CYP11B1 | |
| Trifluoroacetic Acid SCHEMBL29435983 | 0.74 | CYP11B2 (0.35) | CYP11B2PDK2CYP11B1 | |
| SCHEMBL20722091 | 0.74 | NQO2 (0.33) | CYP11B2CYP11B1BACE1 | |
| SCHEMBL29801660 | 0.74 | PSEN1 (0.39) | ATF4KCNH2DPP8DPP9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239937-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118239938-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-111094233-B | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-03-15 | — | — | CN | disclosed |